3KVJ: Crystal Structure of Human Dihydroorotate Dehydrogenase (DHODH) with Amino-Benzoic Acid Inhibitor 105 at 1.94A Resolution

PDB ID: 3KVJDownload
MMDB ID: 80493
PDB Deposition Date: 2009/11/30
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.94  Å
Source Organism:
Similar Structures:
Biological Unit for 3KVJ: monomeric; determined by author and by software (PISA)
Molecular Components in 3KVJ
Label Count Molecule
Protein (1 molecule)
1
Dihydroorotate Dehydrogenase, Mitochondrial
(Gene symbol: DHODH)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
SULFATE IONSULFATE ION
2
1
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
3
1
(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID
4
1
UNDECYLAMINE-N,N-DIMETHYL-N-OXIDEUNDECYLAMINE-N,N-DIMETHYL-N-OXIDE
5
1
ACETATE IONACETATE ION
6
1
2-[(cyclopropylcarbonyl)amino]-5-[methyl(pyridin-3-ylmethyl)amino]benzoic acid2-[(cyclopropylcarbonyl)amino]-5-[methyl(pyridin-3-ylmethyl)amino]benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303